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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1B
All Species:
25.76
Human Site:
S189
Identified Species:
56.67
UniProt:
P16401
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16401
NP_005313.1
226
22580
S189
K
P
K
K
A
T
K
S
P
A
K
P
K
A
V
Chimpanzee
Pan troglodytes
XP_527284
226
22578
S189
K
P
K
K
A
T
K
S
P
A
K
P
K
A
V
Rhesus Macaque
Macaca mulatta
P40286
208
22075
S182
K
G
K
Q
Q
Q
K
S
P
V
K
A
R
A
T
Dog
Lupus familis
XP_545427
211
21163
K189
K
P
K
A
A
K
P
K
A
A
K
P
K
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P43276
223
22558
S186
K
P
K
K
A
A
K
S
P
A
K
P
K
A
V
Rat
Rattus norvegicus
P15865
219
21969
S187
K
A
K
K
A
P
K
S
P
A
K
A
R
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
S190
K
P
K
R
A
A
K
S
P
A
R
A
K
A
V
Chicken
Gallus gallus
P08284
219
22026
S187
R
P
K
K
A
A
K
S
P
A
K
A
K
A
V
Frog
Xenopus laevis
P06892
210
21355
K198
K
A
K
A
A
K
P
K
V
A
K
A
K
K
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
T209
A
A
T
K
A
K
V
T
A
A
K
P
K
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
K195
P
K
T
A
K
P
K
K
P
A
X
K
K
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
52.2
89.3
N.A.
90.7
82.3
N.A.
76.1
72.5
61
N.A.
N.A.
41
N.A.
N.A.
41.5
Protein Similarity:
100
99.5
63.7
91.1
N.A.
92.4
85.8
N.A.
82.7
76.1
68.5
N.A.
N.A.
50.7
N.A.
N.A.
50.8
P-Site Identity:
100
100
46.6
60
N.A.
93.3
73.3
N.A.
73.3
80
40
N.A.
N.A.
53.3
N.A.
N.A.
33.3
P-Site Similarity:
100
100
60
60
N.A.
93.3
80
N.A.
86.6
86.6
40
N.A.
N.A.
60
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
0
28
82
28
0
0
19
91
0
46
0
91
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
73
10
82
55
10
28
73
28
0
0
82
10
82
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
55
0
0
0
19
19
0
73
0
0
46
0
0
0
% P
% Gln:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
10
0
0
0
0
0
0
10
0
19
0
0
% R
% Ser:
0
0
0
0
0
0
0
64
0
0
0
0
0
0
0
% S
% Thr:
0
0
19
0
0
19
0
10
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
64
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _